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Updated: Jan 17, 2026

Augmenting Large Language Models via Vector Embeddings to Improve Domain-Specific Responsiveness
Published on: December 6, 2024
Increasing alignment of large language models with language processing in the human brain
Changjiang Gao1,2, Zhengwu Ma1, Jiajun Chen2
1Department of Linguistics and Translation, City University of Hong Kong, Hong Kong, China.
Larger language models (LLMs) better capture human brain activity during reading than instruction-tuned models. Scaling LLMs, not instruction tuning, improves cognitive plausibility for language comprehension studies.
Area of Science:
- Cognitive Science
- Neuroscience
- Artificial Intelligence
Background:
- Transformer-based large language models (LLMs) offer insights into brain's meaning representation.
- Concerns exist regarding the validity of large LLMs due to extensive data and long context access.
- Instruction tuning is a key LLM technique beyond simple scaling.
Purpose of the Study:
- Investigate if instruction tuning enhances LLMs' ability to capture human brain's linguistic information.
- Compare base and instruction-tuned LLMs of varying sizes against human reading data.
- Assess the cognitive plausibility of LLMs for naturalistic language comprehension.
Main Methods:
- Compared base and instruction-tuned LLMs (varying sizes) with human data.
- Utilized eye-tracking and functional magnetic resonance imaging (fMRI) for brain activity.
- Analyzed data during naturalistic reading tasks.
Main Results:
- Increasing LLM size, rather than instruction tuning, resulted in a closer match to human brain activity.
- Base LLMs showed better alignment with human cognitive processes than instruction-tuned models.
- Model size is a more critical factor than instruction tuning for brain representational similarity.
Conclusions:
- Scaling LLMs is more effective than instruction tuning for mimicking human brain's linguistic processing.
- Findings challenge the cognitive plausibility of instruction-tuned LLMs for studying language comprehension.
- LLM size is a crucial consideration for their application in cognitive neuroscience research.
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