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Updated: Jan 17, 2026
Characterization of Leukocyte-platelet Rich Fibrin, A Novel Biomaterial
Published on: September 29, 2015
Comparative Assessment of the Oral Implant Stability with/without Platelet-rich Fibrin: An In Vivo Study
Mohammad Jalaluddin1, Pavithra K Ramanna2, Veeriah C Jasthi3
1Department of Periodontics and Oral Implantology, Kalinga Institute of Dental Sciences (KIDS), Kalinga Institute of Industrial Technology (KIIT) Deemed to be University, Bhubaneswar, Odisha, India, Phone: +91 9338131843,
Background:
The current investigation aimed to assess oral implant stability with/without platelet-rich fibrin (PRF) using resonance frequency analysis (RFA).
Materials And Methods:
A total of 40 patients, aged 25-55 years, were chosen and their eligibility was examined. There were two groups with 20 patients in each group, Group A: Implant with PRF placement and group B: Implant without PRF placement. Thirty minutes before surgery, the test group's PRF preparation started. After blood collection, for 10 minutes, the tube was centrifuged at 400g at 3,000 revolutions per minute. The PRF was separated and placed in the surgical site for the test group. The implant shoulder up to the interproximal alveolar bone crest served as the reference point. The distance between the implant shoulder and the first visible bone-implant contact was measured using radiography in millimeters to assess the mean marginal bone level changes. All data was collected at baseline, three months, and six months. The stability of the implant was evaluated using RFA. Data was collected and statistically analyzed.
Results:
In an implant with PRF group mean marginal bone level was 12.88 ± 0.28 at baseline, reduced to 9.42 ± 0.12 at 3 months and 8.74 ± 0.06 at the sixth month. In an implant without PRF group mean marginal bone level was 13.02 ± 0.09 at baseline, reduced to 10.96 ± 0.18 at 3 months and 9.44 ± 0.04 at the sixth month. A statistical difference was found within both groups. The mean difference in implant stability was 88.6 ± 1.58 in the implant with PRF group and 72.8 ± 1.20 in the implant without PRF at the end of the sixth month. A statistically significant difference between the groups was noticed.
Conclusion:
In conclusion, the current study showed that the use of PRF during implant surgery improved implant stability compared to the group without PRF.
Clinical Significance:
Clinicians and academics have shifted their focus to making treatment quicker and more comfortable for patients due to the rising success rates of dental implants. A natural concentration of autologous growth factors may be obtained by the preparation of PRF, a straightforward, inexpensive, and minimally invasive technique that is often utilized in several medical specialties to speed up the healing of both soft and hard tissues. How to cite this article: Jalaluddin M, Ramanna PK, Jasthi VC, et al. Comparative Assessment of the Oral Implant Stability with/without Platelet-rich Fibrin: An In Vivo Study. J Contemp Dent Pract 2025;26(5):500-503.
