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Updated: Jan 17, 2026

Palladium N-Heterocyclic Carbene Complexes: Synthesis from Benzimidazolium Salts and Catalytic Activity in Carbon-carbon Bond-forming Reactions
Published on: July 30, 2017
Ligand-free C-H functionalization using a palladium nanocatalyst for the synthesis of 2-phenylindoles and their
Harini G Sampatkumar1, S Likitha2, Maruboina Hemanth Kumar1
1Centre for Nano and Material Sciences, Jain (Deemed-to-be University), Jain Global Campus, Kanakapura, Ramanagaram, Bangalore-562112, India. p.siddappa@jainuniversity.ac.in.
Abstract:
We report a sustainable, magnetically separable Pd@FO-BCN nanocatalyst with minimal Pd loading for efficient ligand-free C-H functionalization in 2-phenylindole synthesis. This novel heterogeneous system shows broad functional group tolerance, high recyclability and excellent yields. Notably, 5-acetyl-2-phenylindole displayed promising anticancer activity, highlighting the nanocatalyst's biomedical relevance and potential for pharmaceutical and materials chemistry applications.

