Related Experiment Video
Updated: Jan 17, 2026
09:53
Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
Published on: July 5, 2021
4.1K
Frailty and Postoperative Outcomes Following Endoscopic Endonasal Skull Base Surgery: A Scoping Review
Sofia E Olsson1,2, Ashleigh Halderman3, Matthew W Ryan4
1Anne Burnett Marion School of Medicine, Texas Christian University, Fort Worth, TX, USA.
Ear, Nose, & Throat Journal
|September 17, 2025
Summary
Frailty assessment, particularly the modified frailty index-5 (mFI-5), can help predict prolonged hospital stays and readmissions after endoscopic endonasal skull base surgery (EESBS). Further research is needed for consistent frailty index use in EESBS outcomes.
Area of Science:
- Neurosurgery
- Otolaryngology
- Geriatric Medicine
Background:
- Frailty is linked to poorer outcomes in surgery.
- Limited understanding exists regarding frailty's impact on endoscopic endonasal skull base surgery (EESBS) outcomes.
Purpose of the Study:
- To conduct a scoping review of existing literature.
- To analyze the relationship between frailty and postoperative outcomes in EESBS.
Main Methods:
- Scoping review methodology employed.
- Searches conducted across multiple databases (PubMed, Cochrane, etc.).
- PRISMA guidelines used for study selection, identifying four relevant studies (2020-2023).
Main Results:
- 1306 patients analyzed; average age 54.1 years.
- Higher modified frailty index-5 (mFI-5) correlated with increased length of stay and readmissions.
- Higher American Society of Anesthesiologists (ASA) classification linked to severe complications and permanent diabetes insipidus.
- Charlson Comorbidity Index (CCI) showed no association with studied complications.
- Frailty had no strong link to surgical complications, endocrine issues, visual outcomes, or quality of life.
Conclusions:
- Frailty indices like mFI-5 may predict specific EESBS postoperative outcomes.
- Further research is required, focusing exclusively on endoscopic endonasal approaches.
- Standardization of frailty indices and analysis methods is crucial for future studies.
Related Concept Videos
01:26Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
574
Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
574
01:30Endoscopic Studies I: Bronchoscopy and Thoracoscopy
537
Endoscopy is a non-surgical medical technique used to examine a person's internal organs and vessels. This lesson will focus on two types of endoscopic studies: bronchoscopy and thoracoscopy.
Bronchoscopy
Description
Bronchoscopy is a procedure that involves direct visualization of the larynx, trachea, and bronchi for diagnostic and therapeutic purposes. A flexible fiber optic or rigid bronchoscope is used to carry out the procedure. The fiber-optic bronchoscope is more frequently used due...
Bronchoscopy
Description
Bronchoscopy is a procedure that involves direct visualization of the larynx, trachea, and bronchi for diagnostic and therapeutic purposes. A flexible fiber optic or rigid bronchoscope is used to carry out the procedure. The fiber-optic bronchoscope is more frequently used due...
537