Related Experiment Video

Updated: Jan 17, 2026

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
06:29

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques

Published on: June 11, 2019

11.0K

Current insights and challenges in the management of left ventricular thrombus

Christos S Katsouras1, Xenofon M Sakellariou2, Aris Bechlioulis2

  • 11st Cardiology Department, University Hospital of Ioannina, Ioannina, Greece; Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece.

Trends in Cardiovascular Medicine
|September 17, 2025
PubMed

Insights

Left ventricular thrombus (LVT) is a serious complication of systolic dysfunction. This review examines current evidence and proposes individualized management strategies for LVT, addressing knowledge gaps in detection and treatment.

Area of Science:

  • Cardiology
  • Cardiovascular Medicine
  • Thrombosis Research

Background:

  • Left ventricular thrombus (LVT) is a significant complication in patients with left ventricular systolic dysfunction.
  • LVT increases the risk of embolic events, such as ischemic stroke, and is associated with higher mortality.
  • Current guidelines recommend 3-6 months of anticoagulation, but evidence is limited.

Purpose of the Study:

  • To review current evidence on left ventricular thrombus identification and management.
  • To identify gaps in the understanding and treatment of LVT.
  • To propose individualized management strategies for LVT.

Main Methods:

  • Systematic review of existing literature on left ventricular thrombus.
  • Analysis of current clinical guidelines and supporting evidence.
  • Identification of areas requiring further research in LVT management.

Main Results:

  • Evidence supporting current LVT management guidelines is derived from small studies with limited generalizability.
  • Key areas needing further study include optimal imaging, anticoagulation choices, duration, and re-evaluation frequency.
  • Individualized strategies are needed, considering patient-specific factors.

Conclusions:

  • Current management of left ventricular thrombus lacks robust evidence for diverse populations.
  • Further research is critical to optimize LVT detection, anticoagulation, and monitoring.
  • Personalized treatment approaches are essential for effective LVT management.

Keywords:
AnticoagulationCardiac magnetic resonanceEchocardiographyEmbolic riskImagingLeft ventricular thrombusRecurrenceResolution

More Related Videos

An In vitro System to Gauge the Thrombolytic Efficacy of Histotripsy and a Lytic Drug07:50

An In vitro System to Gauge the Thrombolytic Efficacy of Histotripsy and a Lytic Drug

Published on: June 4, 2021

3.1K
In Vitro Thrombosis Test for Ventricular Assist Devices09:15

In Vitro Thrombosis Test for Ventricular Assist Devices

Published on: March 21, 2025

1.2K

Related Concept Videos

Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
280
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
329
Mitral Valve Prolapse II: Assessment and Management01:22

Mitral Valve Prolapse II: Assessment and Management

IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular...
438
Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
375
Pulmonary Embolism III: Nursing Management01:27

Pulmonary Embolism III: Nursing Management

A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...
364
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
213