Presentation of Extended-Spectrum Beta-Lactamase-Producing Escherichia Coli Sequence Type 58 Strain (ST58) with Solid Subcutaneous Mass and Hypermucoid Phenotype: A Case Report
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Updated: Jul 17, 2026

Detection of Live Escherichia coli O157:H7 Cells by PMA-qPCR
Published on: February 1, 2014
Miguel Carabaño1, Eunji Jang2, Swapna Charla3
1Department of Pathology and Laboratory Medicine, The Warren Alpert Medical School of Brown University, Providence, RI, USA Mcarabano@brownhealth.org.
Abstract:
Escherichia coli (E. coli) is a versatile bacterium, presenting a wide variety of virulence factors contributing to intestinal and extraintestinal disease. This paper presents a unique case of Escherichia coli strain exhibiting an extended-spectrum beta-lactamase (ESBL) as determined by minimum inhibitory concentration (MIC), identified as sequence type 58 (ST58). The strain, isolated from a clinical specimen, displayed unusual characteristics, forming a solid subcutaneous mass and presenting a hypermucoid phenotype. Comprehensive analysis, including whole-genome sequencing (WGS) and conventional serotyping, was conducted to understand the genetic and phenotypic features of this atypical E. coli strain.
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