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Related Concept Videos

Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...

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Related Experiment Video

Updated: Jun 27, 2026

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
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Bentall Versus David Procedure for Aortic Root Replacement in Patients With Bicuspid Aortic Valve: Systematic Review

Ioannis Zoupas1, Andreas Sarantopoulos2, Nikolaos Schizas1

  • 14(th) Department of Cardiac Surgery, Hygeia Hospital, Athens, Greece.

Heart, Lung & Circulation
|September 17, 2025
PubMed
Summary

For bicuspid aortic valve (BAV) patients, the David operation offers improved survival and fewer complications compared to the Bentall procedure. Freedom from re-operation rates were similar between the two surgical approaches.

Keywords:
BAVBentallBicuspidCompositeDavidRe-implantation

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Area of Science:

  • Cardiovascular Surgery
  • Aortic Root Replacement
  • Bicuspid Aortic Valve Disease

Background:

  • Limited evidence compares valve-sparing aortic root replacement (David procedure) with composite graft replacement (Bentall procedure) in bicuspid aortic valve (BAV) patients.
  • This study addresses the comparative effectiveness of these two aortic root replacement techniques in BAV patients.

Purpose of the Study:

  • To compare overall survival and freedom from re-intervention between the David procedure and the Bentall procedure in patients with BAV.
  • To evaluate postoperative complication rates associated with each surgical approach in BAV patients.

Main Methods:

  • Systematic review and meta-analysis of thirteen studies including 1,264 BAV patients (Bentall) and 602 BAV patients (David).
  • Follow-up period of 8 years.
  • One-stage and two-stage meta-analyses utilized Kaplan-Meier data and a random-effects model, adhering to PRISMA guidelines.

Main Results:

  • The David procedure demonstrated significantly improved overall survival rates compared to the Bentall procedure (HR 0.19, p<0.001).
  • Freedom from re-intervention rates were comparable between the David and Bentall procedures (HR 1.24, p=0.575).
  • Fewer postoperative complications were observed following the David operation.

Conclusions:

  • The David operation is associated with superior survival and reduced complication rates compared to the Bentall procedure in BAV patients.
  • Both procedures showed similar rates of freedom from re-operation.