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Artificial Intelligence-Based Approaches for Brain Tumor Segmentation in MRI: A Review
Khadija Bibi1, Mehmood Nawaz1,2, Sheheryar Khan3
1Department of Biomedical Engineering, The Chinese University of Hong Kong, Sha Tin, Hong Kong SAR, China.
NMR in Biomedicine
|September 17, 2025
Summary
Artificial intelligence, including convolutional neural networks (CNNs) and vision transformers (ViTs), offers automated brain tumor segmentation from MRI scans. These AI methods enhance early diagnosis and treatment by improving tumor identification speed and accuracy.
Area of Science:
- Medical Image Analysis
- Artificial Intelligence in Oncology
- Neuroimaging Techniques
Background:
- Manual brain tumor segmentation in MRI is labor-intensive and requires extensive expertise.
- Automated segmentation using AI is vital for early tumor detection, diagnosis, and treatment planning.
- Advancements in machine learning and deep learning have spurred AI-driven solutions for brain tumor segmentation.
Purpose of the Study:
- To review MRI techniques and popular approaches for brain tumor segmentation.
- To highlight recent advancements in automated brain tumor segmentation.
- To identify challenges and future research directions in the field.
Main Methods:
- Comprehensive literature review of over 200 scholarly publications.
- Analysis of artificial intelligence techniques, including convolutional neural networks (CNNs) and vision transformers (ViTs).
- Examination of network architecture design, segmentation in unbalanced datasets, and multi-modality approaches.
Main Results:
- CNN-based methods and hybrid approaches demonstrate exceptional performance in segmenting brain tumors from MRI data.
- AI techniques significantly improve the speed and accuracy of tumor identification, type, size, and location assessment.
- The study synthesizes key findings from recent research in automated brain tumor segmentation.
Conclusions:
- AI-driven brain tumor segmentation is a rapidly advancing field with significant clinical implications.
- CNNs and hybrid models are highly effective for MRI-based brain tumor segmentation.
- Further research is needed to address existing challenges and explore novel techniques for improved segmentation accuracy and efficiency.

