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Related Experiment Video

Updated: Jan 17, 2026

An Implantable System For Chronic In Vivo Electromyography

An Implantable System For Chronic In Vivo Electromyography

Published on: April 21, 2020

A movable long-term implantable soft microfibre for dynamic bioelectronics.

Ruijie Xie^1,2, Fei Han³, Qianhengyuan Yu¹

¹Guangdong-Hong Kong-Macao Joint Laboratory of Human-Machine Intelligence-Synergy Systems, The Guangdong Provincial Key Laboratory of Robotics and Intelligent System, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.

|September 17, 2025

Summary

This summary is machine-generated.

Researchers developed NeuroWorm, a flexible, movable fiber sensor for long-term bioelectronic monitoring. This innovative device enables precise, in-situ neural signal recording and minimally invasive implantation for advanced human-machine interfaces.

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Area of Science:

Bioelectronics
Neuroscience
Biomaterials

Background:

Long-term implantable bioelectronics are crucial for nervous system evaluation and human-machine interfaces.
Current bioelectronic probes are often immobile and can cause significant tissue response.

Purpose of the Study:

To introduce NeuroWorm, a novel soft, stretchable, and movable fiber sensor for advanced bioelectronic interfaces.
To demonstrate the capability of NeuroWorm for high-quality, long-term, and minimally invasive bioelectrical and biomechanical monitoring.

Main Methods:

Developed a 1D NeuroWorm fiber sensor by rolling 2D bioelectronic devices.
Incorporated longitudinally distributed electrode arrays for multimodal sensing.
Evaluated in-situ signal recording and steerable advancement in biological tissues.
Assessed long-term stability and biocompatibility in rat muscle implantation models.

Main Results:

NeuroWorm successfully recorded high-quality spatio-temporal bioelectrical signals in situ.
The device demonstrated steerable advancement within the brain and on muscle tissue.
Stable bioelectrical monitoring was achieved in rats for over 43 weeks.
Negligible fibroblast encapsulation was observed even after 54 weeks of implantation.

Conclusions:

NeuroWorm represents a significant advancement in bioelectronics, transitioning from immobile probes to active, intelligent devices.
This technology enables long-term, minimally invasive, and mobile evaluation of the nervous system.
The platform holds promise for future applications in neural monitoring and human-machine interfaces.