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Updated: Jan 17, 2026
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An Automated Radiosynthesis of [68Ga]Ga-FAPI-46 for Routine Clinical Use
Published on: May 24, 2024
68 Ga-FAPI-04: A Powerful Tool for Detecting Subcentimeter Metastases of Intrahepatic Cholangiocarcinoma
Yu Sun1, Jianjun Jiang, Qingyuan Meng
1Department of Nuclear Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
None:
A 53-year-old woman presented with subcentimeter liver metastases 18 months after resection of intrahepatic cholangiocarcinoma. 18 F-FDG PET/CT imaging demonstrated no FDG avid in the lesions, whereas 68 Ga-FAPI-04 PET identified 3 metastases with high FAPI uptake. On conventional or contrast-enhanced MRI evaluation, each sequence detected just 1-2 lesions. Our case highlights the advantage and superior sensitivity of 68 Ga-FAPI-04 over 18 F-FDG and MRI in detecting subcentimeter metastases of intrahepatic cholangiocarcinoma.
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