Comparative Study on CPAP Compliance: PAP-NAP Followed by CPAP Trial vs. CPAP Trial Alone.

Area of Science:

• Sleep Medicine
• Respiratory Medicine
• Medical Devices

Background:

• Obstructive sleep apnea (OSA) affects a significant portion of the population.
• Continuous positive airway pressure (CPAP) therapy is a primary treatment for OSA.
• Patient adherence to CPAP therapy remains a challenge, impacting treatment effectiveness.

Purpose of the Study:

• To evaluate the efficacy of a positive airway pressure nap (PAP-NAP) preceding a CPAP trial.
• To compare PAP-NAP followed by CPAP trial versus CPAP trial alone for CPAP adherence in an Asian cohort.
• To explore the relationship between CPAP adherence and polysomnographic data.

Main Methods:

• A cohort of 133 adults diagnosed with OSA was studied.
• Participants were randomized into two groups: one receiving PAP-NAP before CPAP trial, the other receiving CPAP trial only.
• Polysomnographic data and CPAP adherence metrics were collected and analyzed.

Main Results:

• The PAP-NAP group demonstrated superior CPAP compliance (>90%) and adherence (66.64% ± 31.96%) compared to the CPAP-only group (57.90% ± 34.86%).
• Both groups showed a reduction in apnea-hypopnea index (AHI).
• The PAP-NAP group achieved a lower residual AHI, indicating better treatment efficacy.

Conclusions:

• Implementing PAP-NAP prior to a CPAP trial enhances short-term CPAP adherence and aids in mask selection.
• Personalized therapeutic approaches, such as PAP-NAP, can improve patient acceptance and motivation for CPAP therapy.
• Further investigation into the long-term adherence benefits of PAP-NAP is warranted.