Shifts in Demographics and Characteristics Among Patients Leaving Against Medical Advice From Before, During, and

Aaron Shaykevich1, David Yagudayev1, Jamie Romeiser1

  • 1Public Health and Preventative Medicine, State University of New York Upstate Medical University, Syracuse, USA.

Cureus
|September 18, 2025
PubMed

Insights

Discharges against medical advice (AMA) increased among socially disadvantaged and minority patients post-COVID-19, with longer hospital stays and more ICU departures. Targeted interventions are needed to improve trust and outcomes.

Area of Science:

  • Public Health
  • Health Services Research
  • Epidemiology

Background:

  • Discharges against medical advice (AMA) are linked to adverse patient outcomes, including readmission and mortality.
  • The COVID-19 pandemic potentially influenced public trust in healthcare, impacting patient decisions regarding AMA discharges.
  • Understanding demographic shifts in AMA discharges is crucial for public health interventions.

Purpose of the Study:

  • To analyze changes in the demographic and clinical characteristics of patients discharged against medical advice (AMA) before, during, and after the COVID-19 pandemic.
  • To identify temporal associations between the COVID-19 pandemic and the profile of patients with AMA discharges.
  • To inform targeted strategies for reducing AMA discharges and improving patient outcomes.

Main Methods:

  • Retrospective cohort study of 1,560 adult inpatients discharged AMA.
  • Analysis of three distinct time periods: pre-COVID-19, during COVID-19, and post-COVID-19.
  • Bivariate and multinomial logistic regression analyses of demographic variables, Social Deprivation Index (SDI), and comorbidities.

Main Results:

  • Increased proportion of Black patients among AMA discharges during the COVID-19 period compared to pre-pandemic.
  • Extended hospital length of stay prior to AMA discharge observed during and after the pandemic.
  • Higher Social Deprivation Index (SDI) scores associated with AMA discharges in the post-COVID-19 period.
  • Significant increase in AMA discharges originating from the Intensive Care Unit (ICU) after the pandemic.

Conclusions:

  • The COVID-19 pandemic is temporally associated with shifts in the determinants of AMA discharges.
  • Patients discharged AMA post-pandemic are more likely to be socially disadvantaged, from minority backgrounds, have longer hospital stays, and leave from the ICU.
  • There is a need for targeted interventions to enhance patient trust and support, particularly in vulnerable populations, to mitigate AMA discharges and improve health outcomes.
Abstract

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