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Developing 3D Organized Human Cardiac Tissue within a Microfluidic Platform

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Structuring for Success: A Framework for Building a Cardiovascular Center of Excellence.

Adam C Powell^1,2,3, Ronald C Whiting¹, Jacque J Sokolov¹

¹SSB Solutions, Inc., Scottsdale, AZ.

American Journal of Medical Quality : the Official Journal of the American College of Medical Quality

|September 18, 2025

Summary

This summary is machine-generated.

Developing a cardiovascular center of excellence (CVCOE) improves fragmented care. This structured framework optimizes cardiovascular services for better patient outcomes and strategic integration.

Keywords:

COE Center of excellence cardiovascular center of excellence dyad roadmap

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Area of Science:

Health Services Research
Healthcare Management
Cardiovascular Medicine

Background:

Cardiovascular programs face challenges with high costs, fragmentation, and inconsistent governance.
Optimizing cardiovascular service lines is crucial for improving patient care and operational efficiency.

Purpose of the Study:

To present a structured framework for developing a cardiovascular center of excellence (CVCOE).
To enhance care quality and strategic integration within cardiovascular service lines.
To provide a roadmap for aligning investments with evidence-based care and organizational capacity.

Main Methods:

The framework defines a CVCOE through three interdependent layers: foundational infrastructure, clinical pillars, and governance.
A physician-led clinical model integrates business and operating strategies.
A two-stage lifecycle (implementation and maintenance) guides development and quality improvement.

Main Results:

The CVCOE model offers a structured approach to cardiovascular service line optimization.
Implementation experience across diverse settings demonstrates its applicability.
The framework facilitates alignment of structural investments with care delivery.

Conclusions:

The proposed CVCOE framework provides a replicable model for hospitals and health systems.
Embedding leadership and quality systems structurally is key to optimizing cardiovascular services.
This approach creates conditions for improved patient outcomes and operational excellence.