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Targeted Geriatric Assessment to Predict Outcomes in Older Adults With Heart Failure
Caio A M Tavares1, João Otávio Ferreira Meyer2, Scott L Hummel3
1Instituto do Coracao (InCor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, São Paulo, Brazil; Academic Research Organization (ARO), Hospital Israelita Albert Einstein, São Paulo, Brazil; Laboratorio de Investigacao Medica em Envelhecimento (LIM-66), Servico de Geriatria, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, São Paulo, Brazil.
Insights
The 10-minute Targeted Geriatric Assessment (10-TaGA) significantly improves prediction of mortality and hospitalization in older adults with heart failure (HF). This geriatric assessment offers valuable insights beyond standard cardiac evaluations for better patient-centered care.
Area of Science:
- Geriatric Medicine
- Cardiology
- Public Health
Background:
- Heart failure (HF) care in older adults often overlooks geriatric conditions impacting outcomes.
- Standard cardiovascular assessments may not fully capture risks in elderly HF patients.
Purpose of the Study:
- To determine if the 10-minute Targeted Geriatric Assessment (10-TaGA) improves clinical outcome prediction in older adults with HF.
- To evaluate the added value of geriatric assessment in HF patient management.
Main Methods:
- Prospective cohort study of 326 older adults with HF admitted to a geriatric day hospital.
- Cox proportional hazard models analyzed 1-year mortality, hospitalization, and health loss based on 10-TaGA risk tertiles.
- Adjustments were made for clinical variables and the Cardiac and Comorbid Conditions Heart Failure score.
Main Results:
- Higher 10-TaGA risk categories were associated with increased all-cause mortality or hospitalization (HR: 1.97 for high-risk).
- The 10-TaGA also correlated with increased days of health lost.
- Adding 10-TaGA to existing scores improved prediction discrimination for mortality/hospitalization (AUC difference: 0.04).
Conclusions:
- The 10-TaGA provides clinically relevant information beyond standard cardiac assessments in older adults with HF.
- This geriatric assessment tool can support more effective, patient-centered care for elderly HF patients.
- Integrating geriatric assessments can enhance risk stratification and management strategies.
Background:
Health care for older adults with heart failure (HF) has primarily focused on cardiovascular assessment, with limited attention to geriatric conditions that might affect meaningful clinical outcomes.
Objectives:
The purpose of this study was to evaluate whether the 10-minute Targeted Geriatric Assessment (10-TaGA) enhances the prediction of clinical outcomes in older adults with HF.
Methods:
Prospective cohort study of HF patients consecutively admitted to a geriatric day hospital in Brazil. Cox proportional hazard models assessed 1-year all-cause mortality, hospitalization, HF hospitalization, and days of health lost among 10-TaGA score tertiles (low-, intermediate-, and high-risk groups), adjusted for clinical variables and the Cardiac and Comorbid Conditions Heart Failure risk score.
Results:
Among the 326 patients included (mean age 80.9 ± 7.7 years; 37.7% female; 59.8% identified as White), 76 died within 1 year. We observed a graded association between 10-TaGA risk categories and the primary outcome of all-cause mortality or hospitalization (low-risk, reference; intermediate-risk, adjusted HR: 1.41 [95% CI: 0.96-2.05]; high-risk, adjusted HR: 1.97 [95% CI: 1.30-2.99]). Similar trend was found for days of health lost (mean difference of +22 days [95% CI: -2 to +45] and +49 days [95% CI: +9 to +88] for the intermediate- and high-risk groups). Adding the 10-TaGA to clinical variables and the Cardiac and Comorbid Conditions Heart Failure improved discrimination for all-cause mortality/hospitalization (time-specific difference in area under the curve at 1 year: 0.04 [95% CI: 0.01-0.08]; P = 0.025).
Conclusions:
In older adults with HF referred to the geriatric day hospital, the 10-TaGA provided clinically relevant information beyond standard cardiac assessments and may support effective patient-centered care.
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