Effect of temperature and relative humidity on hospitalization for type 2 diabetes mellitus with complications

Although studies have demonstrated the influence of meteorological factors on morbidity and mortality in type 2 diabetes mellitus (T2DM), research focusing specifically on their impact on hospitalization for T2DM with complications remains Limited.This study aimed to investigate the impact of meteorological factors on hospitalization for type 2 diabetes mellitus (T2DM) with complications. The distributed lag nonlinear modelling (DLNM) was used to investigate this effect of temperature and relative humidity (RH) on hospitalization for T2DM with complications. A total of 50,108 T2DM hospitalizations with complications were performed from 2014 to 2019 in Lanzhou, China. Compared to the reference temperature of 12.7 °C, low temperature (-4.1 °C) had harmful effects, with the maximum impact at lag0-1 (cumulative RR = 1.0265, 95% CI: 1.0024,1.0512). High RH (76.70%), compared to the reference of 51.17%, also had hazardous effects, with the maximum impact at lag0-21 (cumulative RR = 1.2307, 95% CI: 1.1265,1.3445). Subgroup analyses showed that low temperature and high RH particularly affected males and individuals aged < 65 years. Low temperature and high RH had a harmful impact on T2DM hospitalizations with complications.