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Updated: Jan 17, 2026

Comparative Study on the Polysaccharide Contents and Antioxidant Activities of Hippophae rhamnoides subsp. sinensis and Hippophae gyantsensis
Published on: August 15, 2025
Plant derived polysaccharides as prebiotic-like components: natural sources of glycolipid regulators and substitutes
Xiaozhen Wang1, Xia Li1, Luyao Zhang1
1Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, School of Pharmaceutical Science and Technology, Faculty of Medicine, Tianjin University, Tianjin 300193, China.
Abstract:
Dietary intervention has gradually become an effective measure to prevent and treat metabolic diseases. Plant-derived polysaccharides (PDPs) can be used as substrates for gut microbiota (GM), directly or indirectly producing beneficial metabolites to show powerful regulation of glucolipid metabolism. This review focuses on mining the key GM of PDPs in exerting the regulatory function of glucolipid metabolism, which provides direction for subsequent personalized diet design. It also exhaustively analyzes the complex crosstalk mechanism of PDPs-gut-host in glycolipid metabolism based on the gut-organ axis, and summarizes and discusses the structure of PDPs with such activities from a new perspective, providing information support for the subsequent discovery of related prebiotics. In addition, some PDPs play a powerful role in replacing sugars and fats without altering or having superior properties to previous foods. This review can provide reference for developing novel prebiotics and probiotics to prevent abnormal glycolipid metabolism.
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