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Related Concept Videos

Growth of Cartilage and Bone Tissue01:27

Growth of Cartilage and Bone Tissue

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Chondrocytes form a temporary cartilaginous model by dividing and secreting a thick gel-like extracellular matrix. Once the chondrocytes undergo programmed cell death, osteoblasts enter the site of the cartilaginous model. The process of replacing the temporary cartilaginous model with bone in an ordered manner is called endochondral ossification. In endochondral ossification, not all of the cartilage is replaced by bone tissue. Some cartilage that performs a protective and supportive function...
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The upper and lower limb initially develops as a small bulge called a limb bud, which appears on the lateral side of the early embryo. The upper limb bud appears near the end of the fourth week of development, with the lower limb bud appearing shortly after.
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Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
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Knee Joint01:23

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Related Experiment Video

Updated: Jan 17, 2026

A Rat Tibial Growth Plate Injury Model to Characterize Repair Mechanisms and Evaluate Growth Plate Regeneration Strategies
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Guided growth for paediatric knee pathology.

Jason Hong1, Brian Loh2

  • 1Monash Health, Melbourne, Australia.

The Knee
|September 18, 2025
PubMed
Summary

Guided growth surgery offers a minimally invasive approach for pediatric knee conditions and lower limb deformities. This review explores its diverse applications, techniques, and outcomes in managing complex pediatric knee pathologies.

Keywords:
Guided growthHemiepiphysiodesisPaediatric kneeReviewTension-band plate

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Last Updated: Jan 17, 2026

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Area of Science:

  • Orthopaedic surgery
  • Paediatric orthopaedics
  • Growth plate modulation

Background:

  • Guided growth has revolutionized paediatric knee surgery.
  • It provides a less invasive alternative for managing knee pathology and lower limb angular deformities.

Purpose of the Study:

  • To systematically review current applications, techniques, and outcomes of guided growth for paediatric knee pathology.
  • To explore future directions in this evolving field of physeal modulation.

Main Methods:

  • Systematic review of guided growth techniques.
  • Examination of physeal modulation for various paediatric knee conditions.

Main Results:

  • Expanded indications for guided growth include coronal plane deformities, patellofemoral instability, osteochondritis dissecans, ACL injuries, meniscal pathology sequelae, and knee flexion deformities.
  • Guided growth is a versatile technique for paediatric knee conditions.

Conclusions:

  • Guided growth is a transformative technique in paediatric knee surgery.
  • Understanding growth plate mechanisms enhances its application in complex paediatric knee pathologies.