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Updated: Jan 17, 2026

Identification of Post-translational Modifications of Plant Protein Complexes
Published on: February 22, 2014
Complex of Proteins Associated with Set1 complexes and their increasing roles in crop improvement
Jun-Yu Chen1, Pan-Yi Zhang1, Cheng-Guo Duan1
1State Key Laboratory of Plant Trait Design, CAS Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai 200032, China; University of the Chinese Academy of Sciences, Beijing 100049, China.
Abstract:
The Complex of Proteins Associated with Set1 (COMPASS) complexes represent a group of highly conserved, multi-subunit complexes that catalyze histone H3 lysine 4 methylation across eukaryotic species. In Drosophila and mammals, COMPASS complexes are classified into distinct subtypes with diverse functions determined by their subunit composition. Plants have evolved analogous COMPASS assemblies that similarly exhibit functional diversification, playing pleiotropic roles in regulating vegetative growth, flowering transition, and stress adaptation. Recent studies have significantly advanced our understanding of the composition, chromatin targeting, and biological functions of plant COMPASS. In this review, we summarize the conserved core components of COMPASS in several plant species, the chromatin targeting strategies, crosstalk with other epigenetic marks, and regulatory role of COMPASS in stress adaptation. We also talk about the researches that may provide clues for crop improvement.
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