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Related Concept Videos

Dementia01:30

Dementia

526
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
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Alzheimer's Disease: Overview01:26

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Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
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Related Experiment Video

Updated: Jan 17, 2026

Author Spotlight: Advancing Alzheimer's Research – Exploring Early Detection and Multi-Omics Approaches
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Predicting dementia through audio: Ensemble and deep learning approaches using acoustic features.

G Priyanka1, K Amshakala2

  • 1Department of M.Tech Computer Science and Engineering, Sri Ramakrishna Engineering College, Coimbatore, India.

Computers in Biology and Medicine
|September 18, 2025
PubMed
Summary
This summary is machine-generated.

Early dementia diagnosis is possible using audio recordings. Machine learning models, particularly Gradient Boost, achieved 90.5% accuracy by analyzing acoustic features like pitch and spectral patterns.

Keywords:
Deep learningDementiaEnsemble learningMFCCSpectral centroid

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Area of Science:

  • Neurology
  • Artificial Intelligence
  • Speech Science

Background:

  • Dementia is a cognitive decline beyond normal aging, affecting memory, reasoning, and daily activities.
  • Communication difficulties are a significant challenge for elderly individuals with dementia.
  • Early diagnosis of dementia is crucial for timely intervention and management.

Purpose of the Study:

  • To investigate the use of audio recordings and machine learning for early dementia diagnosis.
  • To identify key acoustic features indicative of dementia.
  • To compare the performance of ensemble learning and deep learning models in dementia detection.

Main Methods:

  • Extraction of acoustic features (pitch, loudness, spectral centroid, MFCC, F0) from patient audio recordings.
  • Training and evaluation of ensemble models (Random Forest, AdaBoost, XGBoost, Gradient Boost) and deep learning models (BiLSTM, LSTM, CNN-LSTM).
  • Hyperparameter tuning, regularization, and cross-validation were employed to optimize model performance.

Main Results:

  • The Gradient Boost model achieved the highest accuracy of 90.5% in diagnosing dementia using spectral centroid, MFCC, and F0 features.
  • Ensemble learning models demonstrated superior performance over deep learning models in this specific application.
  • The study identified specific acoustic patterns associated with dementia in speech.

Conclusions:

  • Audio analysis combined with machine learning offers a promising avenue for early dementia detection.
  • Gradient Boost and other ensemble methods are effective for diagnosing dementia from speech characteristics.
  • Further research is warranted to understand why ensemble models outperform deep learning in certain scenarios.