Coordinated practice supports a comprehensive approach combining infection prevention and the rational use of antibiotics (RUA), both essential to tackling antibiotic resistance effectively. Over 90% of prescriptions in France are issued in primary care, mainly by general practitioners.

This study analyzes how RUA is integrated into the activities of Professional and Territorial Health Communities (CPTS; Communautés professionnelles territoriales de santé) based on a survey of health care professionals in two CPTS from three French regions chosen for their engagement in national initiatives on antibiotic resistance. A total of 488 health care professionals were selected, with a participation rate of 32,4%.

The results show uneven awareness of RUA and the "One Health" concept among professionals. While antibiotic resistance is perceived as a major issue, its integration into the CPTS's objectives remains limited. The study highlights the need to improve interprofessional coordination and ongoing training to optimize RUA, adapting strategies to each profession's specific needs and strengthening collaboration with regional centers for antibiotic stewardship (CRAtb).

Integrating antibiotic resistance into CPTS missions appears to be a key strategy for effectively addressing this public health issue at the local level.