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Athymic Rat Model for Evaluation of Engineered Anterior Cruciate Ligament Grafts
Published on: March 26, 2015
A Study to Determine the Clinical and Functional Outcomes Following Anatomical Arthroscopic Anterior Cruciate
Anand Kundagol1, G U Kiran1, J Manjunath1
1Department of Orthopedics, SS Institute of Medical Sciences and Research Centre, Davangere, Karnataka, India.
Background:
The anterior cruciate ligament (ACL) plays an important role in stabilising the knee joint. ACL injuries can lead to substantial functional limitations, necessitating surgical intervention for most patients experiencing knee instability and pain.
Objectives:
To assess the clinical and functional outcomes of anatomical arthroscopic ACL reconstruction using a hamstring graft with an adjustable loop and graft retensioning technique.
Materials And Methods:
The present prospective clinical study was carried out on patients, with ACL tears confirmed clinically or radiologically. Following the anatomical arthroscopic ACL reconstruction using a hamstring graft with an adjustable loop and graft retensioning technique, a radiograph was obtained to confirm graft placement. Patients then underwent physiotherapy of the affected knee to restore range of motion, strength, and proprioception. Regular follow-ups were conducted at 1, 3, and 6 months postoperatively, with specific evaluations focussing on active knee flexion of the operated knee.
Results:
In our study, a total of 30 patients were included with the mean age of 36.60 ± 7.58 years. Postoperatively, 43.3% of patients achieved excellent functional outcomes, while 56.7% achieved good outcomes. The Lysholm knee score showed significant improvement from preoperative to postoperative levels (P < 0.05). The range of motion measurements at each follow-up (1, 3, and 6 months) demonstrated significant improvement compared to baseline values (P < 0.05).
Conclusion:
Our study showed that patients who underwent anatomical arthroscopic ACL reconstruction using a hamstring graft achieved good to excellent clinical and functional outcomes. This was accomplished using an adjustable loop fixation technique combined with graft retensioning.
