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Related Experiment Video

Updated: Jan 17, 2026

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
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Published on: August 8, 2025

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Sutureless versus transcatheter aortic valve replacement: propensity matched analysis.

Marie Lamberigts1, Bert Sarrazin1, Delphine Szecel1,2

  • 1Department of Cardiovascular Sciences, Cardiac Surgery, University Hospitals Leuven, Leuven, Belgium.

Expert Review of Medical Devices
|September 19, 2025
PubMed
Summary
This summary is machine-generated.

Sutureless aortic valve replacement (SU-AVR) showed less paravalvular leakage compared to transcatheter aortic valve replacement (TAVR). TAVR offered better hemodynamic performance and shorter hospital stays.

Keywords:
Aortic valve replacementaortic valve stenosispropensity score matchingsutureless aortic valve replacementtranscatheter aortic valve replacement

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Area of Science:

  • Cardiovascular Surgery
  • Interventional Cardiology
  • Medical Device Technology

Background:

  • Aortic valve replacement is a common procedure for severe aortic stenosis.
  • Sutureless aortic valve replacement (SU-AVR) and transcatheter aortic valve replacement (TAVR) are minimally invasive options.
  • Direct comparison of SU-AVR and TAVR using propensity score matching is crucial for understanding patient outcomes.

Purpose of the Study:

  • To compare patient characteristics and postoperative outcomes between SU-AVR and TAVR.
  • To evaluate hemodynamic performance after SU-AVR versus TAVR.
  • To assess complications and mortality rates in a propensity score-matched cohort.

Main Methods:

  • Propensity score matching (PSM) was employed to create comparable groups of patients.
  • A cohort of patients undergoing either SU-AVR or TAVR between October 2017 and June 2022 was analyzed.
  • Postoperative outcomes, including mortality, complications, and hemodynamic parameters, were compared.

Main Results:

  • After PSM, 118 pairs of patients were analyzed. In-hospital mortality was 0% for SU-AVR and 4.2% for TAVR (p=0.063).
  • No significant differences were observed in disabling stroke, need for dialysis, or permanent pacemaker implantation rates.
  • TAVR demonstrated significantly lower transprosthetic gradients but higher rates of moderate or severe paravalvular leakage (11% vs 0%, p<0.001).

Conclusions:

  • TAVR provides superior hemodynamic performance and shorter hospital stays, with reduced need for postoperative dialysis.
  • SU-AVR surgery is associated with significantly less paravalvular leakage.
  • Both SU-AVR and TAVR are viable options, with distinct advantages regarding specific outcomes.