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Author Spotlight: Optimizing Scorpion Venom Extraction for Antivenom Production
Published on: October 6, 2023
Risk-Stratified Observation After Asymptomatic Paediatric Scorpion Envenomation May Safely Reduce Emergency
Inbal Kestenbom1, Shaked Bar-Moshe1, Gidon Test1
1Pediatric Emergency Department, Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.
Insights
Children with mild scorpion envenomation rarely develop delayed symptoms, suggesting shorter emergency department observation times are safe. A risk-stratified approach can optimize care for pediatric scorpion stings.
Area of Science:
- Pediatric Emergency Medicine
- Toxicology
- Clinical Pediatrics
Background:
- Current emergency department (ED) protocols recommend 4-6 hours of observation for pediatric scorpion envenomation.
- Limited evidence supports these guidelines, especially for asymptomatic children.
Purpose of the Study:
- To evaluate the necessity of routine emergency department observation for children with scorpion envenomation.
- To assess the risk of delayed systemic symptoms in pediatric patients with varying envenomation severity.
Main Methods:
- Retrospective cohort study of 287 children in southern Israel over 15 months.
- Utilized a validated envenomation severity score to categorize patients.
- Compared outcomes between Grade 1 (mild) and Grade ≥2 (more severe) envenomation scores.
Main Results:
- 83% of patients had mild envenomation; <1% developed delayed symptoms, with 99% discharged.
- More severe envenomation cases were younger, had higher allergy prevalence, and 94% required hospitalization.
- Delayed symptoms in mild cases resolved with conservative management.
Conclusions:
- A risk-stratified approach considering age, time, allergies, and severity can safely shorten ED observation.
- Children with mild scorpion envenomation symptoms have a low risk of delayed complications.
- Optimizing ED observation time for pediatric scorpion stings is feasible.
Aim:
Current emergency department (ED) protocols in prone regions recommend monitoring for at least 4-6 h after paediatric scorpion envenomation. Since only limited evidence supports these guidelines, particularly for asymptomatic children, we evaluated routine ED observation in these patients.
Methods:
We conducted a retrospective cohort study of southern Israeli children presenting with scorpion envenomation over a 15-month period using a validated envenomation severity score. The primary outcome was the development of delayed systemic symptoms requiring intervention. Children with Grade 1 scores (mild) were compared to those with Grade ≥ 2 scores (more severe).
Results:
Of 287 patients, 238 (83%) presented with mild, and 49 (17%) with more severe envenomation. Less than 1% of mild patients developed delayed symptoms, all of which resolved with conservative management, and 99% were discharged. More severe patients were younger (median age 3.1 vs. 5.8 years), had a higher prevalence of allergy (31% vs. 13%), and 94% developed immediate symptoms requiring hospitalisation.
Conclusion:
A risk-stratified approach taking into consideration age, time since envenomation, history of allergies, and symptom severity could safely reduce ED observation time since children with mild scorpion envenomation symptoms had a low risk of developing significant delayed complications.
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