CompareM2 is a genomes-to-report pipeline for comparing microbial genomes

Area of Science:

• Microbiology
• Bioinformatics
• Genomics

Background:

• Comparative analysis of microbial genomes is crucial for understanding bacterial and archaeal diversity and evolution.
• Existing tools may lack ease of use or comprehensive reporting features for diverse genomic data.

Purpose of the Study:

• To introduce CompareM2, a user-friendly pipeline for the comparative analysis of bacterial and archaeal genomes.
• To provide a streamlined workflow from raw genomic data to a comprehensive, portable report.

Main Methods:

• CompareM2 is a genomes-to-report pipeline.
• It supports analysis of both isolate and metagenomic assembly data.
• The software is designed for single-step installation and execution.

Main Results:

• CompareM2 generates a portable dynamic report document.
• The pipeline facilitates comparative analysis of bacterial and archaeal genomes.
• It simplifies the process of analyzing microbial genomic datasets.

Conclusions:

• CompareM2 offers an accessible and efficient solution for comparative microbial genomics.
• The pipeline's design emphasizes ease of installation and operation.
• It provides valuable insights through dynamic, portable reports.