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Tricuspid Valve Replacement Using the Right Atrial Appendage Valve: Techniques and 1-Year Results
Ahmad Ali Amirghofran1, Seyed Alireza Mirhosseini2,3, Roozbeh Narimani-Javid4
1Cardiovascular Surgery Department, School of Medicine, Shiraz University of Medical Sciences, Zand Street, Shiraz 7134846114, Iran.
Interdisciplinary Cardiovascular and Thoracic Surgery
|September 19, 2025
Summary
This study introduces a new tricuspid valve replacement (TVR) technique using the patient's own right atrial appendage (RAA) tissue. The novel procedure showed promising short-term results with no complications in six patients.
Area of Science:
- Cardiovascular Surgery
- Biomaterials Engineering
- Regenerative Medicine
Background:
- Tricuspid valve replacement (TVR) is complex when repair is not feasible.
- Choosing the optimal substitute for TVR remains challenging.
- Existing prosthetic valves carry risks of complications.
Purpose of the Study:
- To introduce an innovative intraoperative valve construction technique for TVR using native right atrial appendage (RAA) tissue.
- To evaluate the short-term outcomes of this novel TVR approach.
Main Methods:
- Recruited paediatric and adult patients with unrepairable severe tricuspid regurgitation (TR) requiring TVR.
- Harvested patient's RAA tissue for intraoperative reconstruction of a native bileaflet valve.
- Utilized transthoracic echocardiography for pre-operative and 6- and 12-month post-operative assessments.
Main Results:
- Successfully performed the novel TVR procedure on 6 patients (3 with infective endocarditis, 3 with congenital anomalies).
- Achieved successful valve function with no mortality or morbidity.
- Demonstrated stable valve function with no regurgitation or stenosis at 12-month follow-up.
Conclusions:
- The novel tricuspid valve operation using native RAA tissue shows promising short-term efficacy.
- Further investigation with larger patient groups and extended follow-up periods is warranted.
- This technique offers a potential alternative for challenging TVR cases.

