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Updated: Jan 17, 2026

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Genotyping Single Nucleotide Polymorphisms in the Mitochondrial Genome by Pyrosequencing
Published on: February 10, 2023
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mtDNA base editing: Mind the gap
Jose Domingo Barrera-Paez1, Carlos T Moraes2
1MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge, UK.
Molecular Cell
|September 19, 2025
Abstract:
In this issue of Molecular Cell, Xiang et al.1 provided insights into the mechanism and structure-guided engineering of DdCBE for mitochondrial DNA base editing. More precise editing was achieved by better defining the editing window.
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