Related Experiment Video
Updated: Jan 17, 2026

Collection of Human Follicular Fluid, Follicle Somatic Cells, and Immature Oocytes from Individuals Undergoing In Vitro Fertilization
Published on: October 24, 2025
[Fertility preservation for trans men: Barriers and motivations]
Héloise Turck1, Laura Keller2, François Medjkane3
1Département de gynécologie endocrinienne et de médecine de la reproduction, CHU Lille, hôpital Jeanne-de-Flandre, avenue Eugène-Avinée, 59000 Lille, France.
Trans men (female-to-X individuals) face barriers to oocyte preservation due to medical and psychological factors. Improving information and healthcare provider training is crucial for fertility options.
Area of Science:
- Reproductive Medicine
- Gender Affirming Care
- Bioethics
Background:
- Oocyte preservation is a vital fertility option for transgender men (female-to-X individuals).
- Despite available information, uptake remains low, necessitating investigation into underlying reasons.
Purpose of the Study:
- To identify motivations and barriers for oocyte preservation in trans men undergoing gender transition.
- To inform improvements in fertility care pathways for this population.
Main Methods:
- Observational, cross-sectional study (TRANSPF) at Lille University Hospital (May 2018-May 2024).
- Online questionnaire assessing demographics, care pathways, knowledge, motivations, and barriers.
- Descriptive statistical analysis of data from 67 participants.
Main Results:
- Only 8.5% of trans men underwent oocyte cryopreservation, below the national average.
- Key motivations included potential use of the ROPA method (45%).
- Significant barriers: interrupting androgen therapy (45%), transvaginal retrieval (46%), protocol burden (37%), and fear of poor medical reception (31%).
Conclusions:
- Enhanced, inclusive information on fertility preservation is essential for trans men.
- Addressing psychological, technical, and legal barriers is critical within transition care.
- Improved healthcare provider training and bioethical discussions are needed to enhance access to fertility options.
Related Concept Videos
Infertility in Males
Infertility in Females
Endometriosis, a condition characterized by abnormal growth of...
Spermatogenesis
Birth Control Methods
Factors Affecting Drug Distribution: Physiological Barriers
The capillary endothelial barrier allows only smaller molecules below 600 Da (Daltons) to pass through. It also restricts drugs like heparin that are bound to blood components, limiting their movement within the bloodstream.
The...
Testosterone: Functions and Regulation

