Stereotactic body radiotherapy for lung cancer: a review

Stereotactic body radiation therapy (SBRT) is a radiotherapy technique that has been widely adopted in clinical settings for lung cancer treatment since the 1990s. In this study, we reviewed the medical history and current standard techniques of SBRT. Previous clinical studies on lung cancer, including those conducted by Japan Clinical Oncology Group, have demonstrated high local control rates with acceptable toxicities. Current indications for SBRT include expanded inoperable peripheral lung cancer to include operable, central, or oligometastatic lung cancer. We also reviewed the past and ongoing international clinical trials.