Related Experiment Video
Updated: Jan 17, 2026

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
Published on: August 12, 2020
Fetal, Neonatal, and Pediatric Immunology
1Vetmeduni, Department of Small Animals and Horses, Clinical Center for Reproduction, Veterinärplatz 1, A-1210 Vienna, Austria.
Abstract:
Although considerable progress has been made in understanding the development of the maternal, fetal, and neonatal immune systems, many questions remain. In this review, some old and new achievements are discussed. During pregnancy, cats and dogs show some discrepancies; however, in both species, a transient immunosuppression enables establishment of pregnancy. The innate immune system is supported by maternally derived antibodies, which provide some defense against infection by passive transfer of immunoglobulins. Some measures to increase neonatal immune defense, such as natural and artificial hyperimmune solutions, paraimmunity inducers, and vaccinations, will be discussed.
Related Concept Videos
Development of Immunocompetence
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
Pharmacokinetics in Pediatric Patients: Drug Distribution
Pharmacokinetics in Pediatric Patients: Drug Excretion
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption
Pharmacokinetics in Pediatric Patients: Drug Metabolism
Drug Dosing: Infants and Children

