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Updated: Jan 17, 2026

Determination of Reproductive Competence by Confirming Pubertal Onset and Performing a Fertility Assay in Mice and Rats
Published on: October 13, 2018
Canine Puberty
Fiona Hollinshead1, Xianfei Sun2, Michelle Aono2
1Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA.
None:
Canine puberty is a complex developmental process driven by neuroendocrine regulation and hormonal changes that establish reproductive capability. The maturation of the hypothalamic-pituitary-gonadal axis triggers gametogenesis and reproductive hormone production, with significant variations based on breed, body weight, metabolic status, and environmental factors. Puberty onset differs between males and females, requiring distinct diagnostic criteria. Understanding these factors is essential for breeding management, optimizing reproductive health, and determining the appropriate time for neutering. This study synthesizes current research to provide veterinarians with practical insights into canine reproductive physiology and its clinical applications.
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