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Updated: Jan 17, 2026

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
Published on: May 17, 2024
Response to: Survival after risk-reducing mastectomy in young BRCA1 carriers with breast cancer
Virginia Delucchi1, Matteo Lambertini2,3, Eva Blondeaux1
1U.O. Epidemiologia Clinica, IRCCS Ospedale Policlinico San Martino, Genova, Italy.
Abstract:
We address methodological considerations in evaluating risk-reducing mastectomy among young BRCA carriers with prior history of breast cancer, emphasizing time-dependent analysis, realistic assumptions on mortality and contralateral breast cancer risk, and appropriate confounder adjustment as ways to improve accuracy in survival outcome estimates.
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