Related Experiment Video
Updated: Jan 17, 2026

Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children
Published on: August 22, 2012
Recent advances in nanoformulations for helminthiasis treatment
João Paulo Figueiró Longo1, Josué de Moraes2,3
1Departamento de Genética e Morfologia, Instituto de Ciências Biológicas, Universidade de Brasília, Brasília, Brazil.
Introduction:
Recent advances in nanoformulations are reshaping the treatment landscape for helminthiasis by addressing critical challenges such as drug resistance, poor bioavailability, and off-target effects.
Areas Covered:
This review examines current innovations in nanotechnology applied to anthelmintic therapy, with a particular focus on lipid- and polymer-based systems designed to enhance drug solubility, stability, and targeted delivery. A comprehensive literature search was performed to identify recent developments, highlight preclinical and translational studies, and evaluate the performance of solid lipid nanoparticles, nanoemulsions, and self-nanoemulsifying drug delivery systems. Relevant articles were retrieved from peer-reviewed journals indexed in PubMed, Scopus, and Web of Science, covering publications up to June 2025.
Expert Opinion:
The integration of nanotechnologies into helminthiasis treatment offers promising therapeutic advantages but faces important challenges related to industrial scalability, regulatory approval, and implementation in low-resource settings. Addressing these issues requires coordinated efforts between academia, industry, and public health stakeholders. The review outlines key considerations for technology transfer and commercialization, underscoring the importance of cost-effectiveness, patient acceptability, and cross-sector collaboration to ensure the successful translation of nanomedicine-based solutions for neglected tropical diseases.
More Related Videos
05:19Evaluation of Antioxidant and Anthelmintic Properties of Tithonia diversifolia Extracts Against Gastrointestinal Nematode Eggs Using In Vitro Assays
Published on: August 1, 2025
08:18Self-Nanoemulsification of Healthy Oils to Enhance the Solubility of Lipophilic Drugs
Published on: July 27, 2022
Related Concept Videos
Bioavailability Enhancement: Drug Permeability Enhancement
Factors Affecting Dissolution: Particle Size and Effective Surface Area
Drugs for Treatment of Diarrhea-Predominant IBS
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
Fungal Phylum Microsporidia
Bioavailability Enhancement: Drug Stability Enhancement and GI Retention