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Related Experiment Video

Updated: Jan 17, 2026

High-density Electroencephalographic Acquisition in a Rodent Model Using Low-cost and Open-source Resources
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Wireless high-density electroencephalography in the perioperative setting.

Nathan Runstadler1, Selena Martinez1, UnCheol Lee2

  • 1Department of Anesthesiology, Michigan Medicine, Ann Arbor, MI, USA.

Journal of Neuroscience Methods
|September 20, 2025
PubMed
Summary
This summary is machine-generated.

High-density wireless electroencephalography (EEG) offers a practical solution for monitoring brain activity during surgery. This advanced system provides detailed neuroanatomical insights into perioperative brain states, improving patient care.

Keywords:
ElectroencephalographyNeuroanesthesiaNeurophysiological monitoringPerioperative periodWireless technology

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Area of Science:

  • Neuroscience
  • Anesthesiology
  • Medical Devices

Background:

  • Current operating room electroencephalography (EEG) systems are limited to frontal channels, restricting neuroanatomical understanding of perioperative brain states.
  • There is a need for comprehensive, whole-scalp EEG analysis during the perioperative period.

Purpose of the Study:

  • To present practical strategies for implementing whole-scalp, high-density EEG systems in the perioperative setting.
  • To enable more comprehensive neuroanatomical analysis of perioperative brain states.

Main Methods:

  • Implementation of a wireless, 72-channel high-density EEG system in the CAPACHINOS-2 clinical trial.
  • Assessment of placement time, impedance, and data quality.
  • Establishment of data acquisition and analysis pipelines, including source localization.

Main Results:

  • Successful acquisition of high-density wireless EEG data from 45 participants.
  • Median placement time of 34 minutes.
  • Lower preoperative median impedance values (13 kΩ) compared to low-density systems (39 kΩ).
  • Demonstration of more complex connectivity and broader cortical alpha rhythm distribution under anesthesia.

Conclusions:

  • Wireless high-density EEG is a feasible and promising tool for perioperative neurophysiologic monitoring.
  • This technology enhances understanding of altered brain states with high spatiotemporal resolution.