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The Role of Gender in Blunt Thoracic Aortic Injuries
Ilenia D'Alessio1, Nicola Monzio-Compagnoni1, Greta Salinetti2
1Division of Vascular Surgery, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Annals of Vascular Surgery
|September 21, 2025
Summary
Gender influences blunt thoracic aortic injury (BTAI) severity and treatment outcomes. While men experience more severe injuries, women undergoing thoracic endovascular aortic repair (TEVAR) face higher complication risks.
Area of Science:
- Trauma Surgery
- Vascular Surgery
- Medical Research
Background:
- Blunt thoracic aortic injuries (BTAIs) are a significant cause of mortality in polytrauma patients.
- Males in their fifth decade are most commonly affected by BTAIs.
- Thoracic endovascular aortic repair (TEVAR) is the standard treatment, but gender's impact remains unclear.
Purpose of the Study:
- To investigate gender-related differences in BTAI severity.
- To determine if gender affects perioperative outcomes following TEVAR.
Main Methods:
- Retrospective analysis of the Aortic Trauma Foundation Global Registry.
- Inclusion of 623 patients meeting study criteria.
- Assessment of BTAI severity using Society for Vascular Surgery classification and analysis of TEVAR complications.
Main Results:
- Males had a higher likelihood of developing more severe BTAIs (OR 1.500, P=0.035).
- TEVAR was performed in 384 patients.
- Women showed a trend towards increased intraoperative and perioperative complications after TEVAR, though not statistically significant (P > 0.05).
Conclusions:
- Gender influences BTAI natural history and TEVAR outcomes.
- Females have a lower risk of severe BTAIs but appear to experience more complications post-TEVAR.
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