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Updated: Jan 17, 2026

Generation of Electronic Cigarette Aerosol by a Third-Generation Machine-Vaping Device: Application to Toxicological Studies
Published on: August 25, 2018
Pre-existing pulmonary arterial hypertension decompensation associated with e-cigarettes in an adolescent
James Andrew Bishara1, Patrick Evers1
1Oregon Health and Science University, Doernbecher Children's Hospital, Department of Pediatrics, Division of Pediatric Cardiology, Portland, OR, USA.
Abstract:
An adolescent girl with a long-standing history of pulmonary arterial hypertension experienced severe clinical decompensation after starting to use e-cigarettes. A combination of e-cigarette cessation, atrial septostomy, increasing treprostinil, and initiation of sotatercept led to clinical improvement. Her new baseline was improved over her pre-e-cigarette baseline.
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