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Commentary on: Inhibition of LINC00707/miR-223-3p/FKBP5 axis has a protective effect on diabetic kidney disease

Yirui Zhao1, Fengyue Zhang1

  • 1Department of Nephrology, The Third Clinical College of Shanxi University of Chinese Medicine, Taiyuan, Shanxi, China.

Journal of Diabetes Investigation
|September 22, 2025
PubMed
Abstract

No abstract available in PubMed .

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Diabetic Nephropathy01:28

Diabetic Nephropathy

Definition Diabetic nephropathy is a chronic kidney complication that results from prolonged hyperglycemia.Prevalence It is the most common cause of chronic kidney disease (CKD) and end-stage renal disease (ESRD) worldwide, affecting up to half of individuals with diabetes.Pathophysiology • Sustained hyperglycemia triggers multiple hemodynamic and metabolic changes in the kidney. • Early in the disease, increased renal blood flow and glomerular hyperfiltration occur due to afferent arteriolar...

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