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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
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Author Spotlight: Unraveling the Molecular Mechanisms in PCO and Fibrosis Following Cataract Surgery
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Bilateral Cystoid Macular Edema After Light Treatment With Light-Adjustable Lens.

Fatma Shakarchi1,2, Evelyn Bassett2, Ayorinde Cooley1,2

  • 1Ophthalmology, Willis-Knighton Medical Center, Shreveport, USA.

Cureus
|September 22, 2025
PubMed
Summary

This study reports the first case of bilateral cystoid macular edema (CME) after light-adjustable lens (LAL) implantation and ultraviolet (UV) light adjustment. Prompt treatment with anti-inflammatory drops resolved the CME.

Area of Science:

  • Ophthalmology
  • Biomedical Engineering

Background:

  • Light-adjustable lenses (LALs) offer adjustable visual acuity (VA) post-cataract surgery via ultraviolet (UV) light therapy.
  • UV-induced cystoid macular edema (CME) is a poorly documented complication associated with LALs.
Keywords:
case reportcataractcystoid macular edemalallight-adjustable intraocular lenses

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