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Related Experiment Video

Updated: Jul 25, 2026

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Advances in endoscopic closure techniques for endoscopic full-thickness resection.

Meng Zhang1, Jiao Liu1, Jiang-Ning Gu1

  • 1Department of Endoscopy, General Hospital of Northern Theater Command, Shenyang 110016, Liaoning Province, China.

World Journal of Gastrointestinal Endoscopy
|September 22, 2025
PubMed
Summary

Endoscopic full-thickness resection (EFTR) requires effective wound closure. This review evaluates current endoscopic suturing techniques for EFTR defects, assessing their efficacy and clinical use.

Keywords:
Closing devicesEndoloopEndoscopic clip closure techniqueEndoscopic full-thickness resectionEndoscopy closure

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Area of Science:

  • Gastroenterology
  • Endoscopic Surgery
  • Medical Device Innovation

Background:

  • Endoscopic full-thickness resection (EFTR) is increasingly used clinically.
  • Successful wound closure is critical for EFTR procedures.
  • Traditional methods like clips and sutures have evolved into innovative techniques.

Purpose of the Study:

  • To systematically evaluate current endoscopic closure techniques for EFTR-induced defects.
  • To assess the efficacy, limitations, and clinical applicability of these techniques.
  • To highlight advancements in specialized endoscopic suturing devices.

Main Methods:

  • Systematic review of current literature on endoscopic closure techniques post-EFTR.
  • Evaluation of efficacy and limitations based on published data.
  • Analysis of clinical applicability and technological innovation in suturing devices.

Main Results:

  • Various endoscopic suturing techniques have been developed beyond initial clip and nylon thread methods.
  • Ongoing innovation is leading to specialized devices for EFTR wound closure.
  • Efficacy and limitations vary across different techniques and devices.

Conclusions:

  • Endoscopic closure is a key factor in successful EFTR.
  • A range of innovative techniques and devices are available for managing EFTR defects.
  • Further evaluation is needed to determine optimal techniques for diverse clinical scenarios.