Related Experiment Video
Updated: Jan 17, 2026
04:04
Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer
Published on: February 12, 2017
10.9K
Integrative Supportive Care Trial to Enhance Physical Activity in Malignant Pleural Effusion-Protocol for the
Bianca M Iacopetta1,2,3, Chloe Charlesworth2,4, Emily Jeffery5
1Institute for Respiratory Health, Pleural Medicine Unit Perth Australia.
Respirology Case Reports
|September 22, 2025
Summary
This study investigates an integrative supportive care program for malignant pleural effusion (MPE) patients. The program aims to improve physical activity and quality of life by addressing malnutrition, psychological well-being, and exercise needs.
Area of Science:
- Oncology
- Palliative Care
- Clinical Trials
Background:
- Malignant pleural effusion (MPE) is linked to advanced cancer, poor patient outcomes, and significant symptom burden.
- Patients with MPE experience weight loss, fatigue, breathlessness, distress, and anxiety, limiting daily activities.
- Patient and carer priorities include symptom freedom and maintaining daily life activities.
Purpose of the Study:
- To evaluate the effectiveness of an integrative supportive care program for patients with malignant pleural effusion.
- To assess the impact of a multidisciplinary supportive care intervention on physical activity levels in MPE patients.
Main Methods:
- A randomized controlled trial (ISC-TEAM study) involving 100 participants with MPE.
- Participants were assigned to standard care or an individualized 12-week integrative supportive care program (dietetics, exercise physiology, psychological support).
- Telehealth consultations were provided at weeks 1, 4, and 8. Primary outcome: device-assessed daily physical activity (steps/day).
Main Results:
- The primary outcome is device-assessed daily physical activity (steps/day).
- Secondary outcomes include quality of life, malnutrition risk, psychopathology, symptoms, physical activity profile, and program acceptability and compliance.
Conclusions:
- This randomized trial will evaluate the effects of a multidisciplinary supportive care program in MPE.
- The program aims to improve participants' ability to engage in physical activities and enhance overall well-being.
Related Concept Videos
01:28Pleural Effusion II: Symptoms and Management
660
Pleural Effusion Overview
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
660
01:25Pleural Effusion I: Introduction
4.0K
Pleural effusion is an abnormal fluid accumulation in the pleural cavity, a narrow space between the lungs and the chest wall. It is not a disease per se but rather a symptom or indication of an underlying disease. In normal circumstances, this space contains a small amount of fluid (5 to 15 mL), a lubricant facilitating the non-frictional movement of the pleural surfaces.
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's...
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's...
4.0K
01:26Flail Chest-II
540
Managing flail chest, a condition characterized by a segment of the chest wall moving independently from the rest of the thoracic cage, requires a comprehensive approach. It includes a thorough assessment of the patient's condition, a diagnostic evaluation to determine the extent of the injury, and the implementation of appropriate medical interventions tailored to the individual's needs.
Assessment:
1. Clinical Evaluation:
History:
Assessment:
1. Clinical Evaluation:
History:
540
01:29Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
329
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
329
01:27Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
3.1K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
Medical History
3.1K
01:24Chest Physiotherapy
1.7K
Chest Physiotherapy (CPT) is a therapeutic technique used in respiratory care to improve ventilation, clear bronchial secretions, and enhance the efficiency of respiratory muscles. This therapy includes three primary procedures: postural drainage, percussion, and vibration. It can be performed on spontaneously breathing patients and those who are intubated and mechanically ventilated.
Purpose
CPT is primarily used for patients with excessive bronchial secretions who have difficulty clearing...
Purpose
CPT is primarily used for patients with excessive bronchial secretions who have difficulty clearing...
1.7K