Multivalvular infective endocarditis due to streptococcus pluranimalium in a young patient with bicuspid aortic valve

Multivalvular infective endocarditis (MIE) is an uncommon condition associated with increased morbidity and mortality compared to single-valve involvement. We present the case of a young patient with a bicuspid aortic valve and MIE affecting both the aortic and mitral valves, caused by Streptococcus pluranimalium. Timely diagnosis, targeted antibiotic therapy, and surgical intervention with dual-valve replacement led to a favorable clinical outcome. This case highlights the importance of considering the diagnosis of infective endocarditis in young patients presenting with fever and constitutional symptoms without an apparent cause and initiating the investigation of an underlying congenital heart disease. It also highlights that uncommon pathogens may be etiological agents of infective endocarditis in patients with predisposing valvular abnormalities.