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Purulent pericarditis caused by Nocardia: a case report and literature review

Xinxin Zhong1, Ao Lin2, Fu Cao1

  • 1Department of Pulmonary and Critical Care Medicine, Red Cross Hospital of Yulin City, Yulin, Guangxi, China.

Frontiers in Cardiovascular Medicine
|September 22, 2025
PubMed

Insights

Nocardia infection causing purulent pericarditis is rare and often misdiagnosed. Prompt identification through pericardial fluid culture and targeted antibiotics are crucial for successful treatment, especially in immunocompromised patients.

Area of Science:

  • Infectious Diseases
  • Cardiology
  • Immunology

Background:

  • Purulent pericarditis is a severe condition with high mortality.
  • Nocardia species are opportunistic pathogens that can cause severe infections.
  • Nocardia-induced purulent pericarditis is rare and often misdiagnosed as tuberculosis or other bacterial infections, particularly in patients with acquired immune deficiency syndrome (AIDS).
Keywords:
AIDSNocardiaantibiotic therapypericardiocentesispericarditis

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