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Combined Novel Microfocused Ultrasound and Microneedle Fractional Radiofrequency System for Multilayered Facial
Ruiyao Wang1, Guangling Peng2, Yangmei Chen1
1Department of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Journal of Cosmetic Dermatology
|September 22, 2025
Summary
Combining microfocused ultrasound (MFU) and microneedle fractional radiofrequency (MFR) offers a safe and effective facial rejuvenation treatment. This dual therapy significantly improves skin tightening, texture, and pore appearance in a single session.
Area of Science:
- Dermatology
- Aesthetic Medicine
- Cosmetic Procedures
Background:
- Growing demand for non-invasive anti-aging skin treatments due to an aging global population.
- Need for advanced therapies to address facial laxity and photoaging.
- Development of novel combination treatments for enhanced rejuvenation outcomes.
Purpose of the Study:
- To assess the safety and efficacy of combining microfocused ultrasound (MFU) with microneedle fractional radiofrequency (MFR) for facial rejuvenation.
- To compare the outcomes of combined MFU and MFR therapy against a control side on the same face.
- To evaluate the impact of the combined treatment on various facial aging parameters.
Main Methods:
- A study involving 26 patients with facial laxity.
- Each patient received simultaneous MFU and MFR treatments on one side of the face.
- Assessment of facial photoaging using VISIA imaging, ultrasound for fat thickness, and subjective evaluations at 0, 1, and 3 months.
Main Results:
- Significant improvements in skin texture, wrinkles, pores, spots, and redness observed with combined MFU and MFR.
- Reduction in subcutaneous fat thickness noted, particularly in the masseter and mid-cheek areas.
- High patient satisfaction (over 90%) with mild, transient side effects.
Conclusions:
- Combined MFU and MFR therapy is a safe and effective method for facial rejuvenation.
- The synergistic approach enhances skin tightening, depigmentation, and pore refinement.
- This combination treatment provides superior results within a single session.
Keywords:
clinical researchfacial rejuvenationmicrofocused ultrasoundmicroneedle fractional radiofrequency
