Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Obesity01:24

Obesity

1.1K
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
1.1K
Drug Dosing: Obese Patients01:21

Drug Dosing: Obese Patients

225
In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
225
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution01:25

Pharmacokinetics in Obese Patients: Drug Absorption and Distribution

248
Obesity significantly alters the pharmacokinetic processes of drug absorption and distribution, presenting unique challenges in medical treatment. The increased fat tissue and decreased lean muscle in obese individuals can significantly affect how drugs are absorbed into the body and distributed across different tissues. This alteration can lead to variances in the effectiveness and safety of medications, necessitating adjustments in dosing or drug selection for obese patients.One notable...
248
Binge Eating Disorders01:23

Binge Eating Disorders

426
Binge eating disorder is a significant mental health condition characterized by recurrent episodes of excessive food consumption within a short period, accompanied by a perceived loss of control over eating behavior. Unlike occasional overeating, binge eating disorder is marked by distressing emotions such as guilt, shame, and anxiety following binge episodes. The disorder affects individuals across different ages and backgrounds, with profound implications for physical and psychological...
426
Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion01:20

Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion

169
Drug metabolism, a critical process in the liver, involves two primary phases: Phase I reactions and Phase II conjugation. Obesity introduces significant alterations in this metabolic process, primarily due to fatty infiltration of the liver, leading to conditions such as nonalcoholic fatty liver disease (NAFLD). This condition can modify the activities of both Phase I and II enzymes, impacting how drugs are metabolized in obese patients.Phase I metabolism sees variable effects across...
169
Bulimia Nervosa01:30

Bulimia Nervosa

692
Bulimia nervosa is a complex and severe eating disorder characterized by a cyclical pattern of binge-and-purge eating pattern. It generally involves an episode of binge eating, followed by compensatory behaviors such as vomiting, excessive exercise, laxative use, or fasting, to prevent weight gain. Despite often maintaining a normal weight, individuals with bulimia are intensely preoccupied with their body image and harbor an overwhelming fear of gaining weight. This can contribute to the...
692

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Identifying Predictors of Weight-Related Outcomes With Fixed-Dose, Extended-Release Naltrexone and Bupropion Among Treatment-Adherent Patients in Phase 3 COR Trials: A Treatment Target Analysis.

Obesity science & practice·2026
Same author

GLP-1 and Nutrient Stimulated Hormone Targets: Beyond Weight Loss.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]·2026
Same author

TOS/OMA/OAC Expert Guidance Statement on Obesity Pharmacotherapy: A Humbling Call to Action.

Obesity (Silver Spring, Md.)·2026
Same author

Clinical and Preclinical Obesity in Korean Adults from 2014 to 2023.

Diabetes & metabolism journal·2026
Same author

Semaglutide and Hospitalizations in Patients With Obesity and Established Cardiovascular Disease: An Exploratory Analysis of the SELECT Randomized Clinical Trial.

JAMA cardiology·2025
Same author

Once-Monthly Maridebart Cafraglutide in Obesity - A Phase 2 Trial. Reply.

The New England journal of medicine·2025
Same journal

The Clinical Impact of Patient Embarrassment in Gynecology: A Comprehensive Review of Barriers, Consequences, and Mitigation Strategies.

Medical sciences (Basel, Switzerland)·2026
Same journal

Physical Performance as a Predictor of Length of Hospital Stay in Patients Undergoing Open-Heart Surgery: A Multicenter Prospective Study.

Medical sciences (Basel, Switzerland)·2026
Same journal

Renal Involvement in Pediatric Small-Vessel Vasculitis: A Comprehensive Review of Clinical Impact, Diagnosis, and Management.

Medical sciences (Basel, Switzerland)·2026
Same journal

MRI-Based Radiomics and Artificial Intelligence for Prediction of Recurrence and Prognostic Outcomes in Oral Tongue Squamous Cell Carcinoma: A Systematic Review with Functional Meta-Synthesis.

Medical sciences (Basel, Switzerland)·2026
Same journal

Present and Future Options for Pharmacotherapy in Cardiovascular Disease: Hemodynamic and Mechanistic Therapeutic Targets.

Medical sciences (Basel, Switzerland)·2026
Same journal

Narrative Review of Digital Twins in the Health Domain: Development, Application, and Evidence Consolidation.

Medical sciences (Basel, Switzerland)·2026
See all related articles

Related Experiment Video

Updated: Jan 17, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
05:10

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

909

Beyond Obesity.

George A Bray1, Donna H Ryan1

  • 1Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA.

Medical Sciences (Basel, Switzerland)
|September 22, 2025
PubMed
Summary
This summary is machine-generated.

New diagnostic categories for obesity, including "Preclinical Obesity," are proposed. This aims to improve diagnosis beyond body mass index (BMI) by considering fat distribution and function, potentially using terms like "adiposity."

Keywords:
body mass index (BMI)central fatclinical obesitystigma of obesity

More Related Videos

A Chronic High-Intensity Interval Training and Diet-Induced Obesity Model to Maximize Exercise Effort and Induce Physiologic Changes in Rats
06:28

A Chronic High-Intensity Interval Training and Diet-Induced Obesity Model to Maximize Exercise Effort and Induce Physiologic Changes in Rats

Published on: April 28, 2023

1.3K
An Acupoint Catgut-embedding Therapy for Treating Obesity
04:50

An Acupoint Catgut-embedding Therapy for Treating Obesity

Published on: April 4, 2025

1.3K

Related Experiment Videos

Last Updated: Jan 17, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
05:10

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

909
A Chronic High-Intensity Interval Training and Diet-Induced Obesity Model to Maximize Exercise Effort and Induce Physiologic Changes in Rats
06:28

A Chronic High-Intensity Interval Training and Diet-Induced Obesity Model to Maximize Exercise Effort and Induce Physiologic Changes in Rats

Published on: April 28, 2023

1.3K
An Acupoint Catgut-embedding Therapy for Treating Obesity
04:50

An Acupoint Catgut-embedding Therapy for Treating Obesity

Published on: April 4, 2025

1.3K

Area of Science:

  • Medical Diagnostics
  • Public Health
  • Metabolic Disorders

Background:

  • Obesity diagnosis has evolved from life insurance tables to body mass index (BMI).
  • BMI has limitations and the epidemic of obesity necessitates improved diagnostic tools.
  • Fat distribution and function are critical aspects of obesity, pioneered by Jean Vague.

Purpose of the Study:

  • To discuss improved diagnostic methods for increased body fat and abnormal distribution.
  • To explore alternative terminology for obesity, such as adiposity or healthy weight.
  • To address the limitations of current obesity diagnostic criteria and the need for new guidelines.

Main Methods:

  • Review of historical diagnostic criteria for obesity.
  • Discussion of the limitations of body mass index (BMI).
  • Exploration of the role of fat distribution and function in obesity.

Main Results:

  • A proposal for a new diagnostic category, "Preclinical Obesity."
  • Highlighting the need for diagnostic guidelines beyond BMI.
  • Identifying "adiposity" and "healthy weight" as potential alternative terms.

Conclusions:

  • Current diagnostic methods for obesity, primarily BMI, are insufficient.
  • New diagnostic guidelines are needed to account for fat distribution and function.
  • Alternative terminology like "adiposity" may reduce stigma associated with obesity.