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Learning Collaborative to Support Continuous Quality Improvement in Newborn Screening.

Elizabeth Jones1, Sikha Singh1, Sarah McKasson1

  • 1Association of Public Health Laboratories, 7700 Wisconsin Avenue, Suite 1000, Bethesda, MD 20814, USA.

International Journal of Neonatal Screening
|September 22, 2025
PubMed
Summary
This summary is machine-generated.

Continuous quality improvement (CQI) initiatives effectively enhanced newborn screening (NBS) programs. A collaborative, data-driven approach improved timeliness and diagnosis confirmation for infants, demonstrating the success of NBS quality improvement projects.

Keywords:
NewSTEPsassociation of public health laboratories (APHL)collaborativecontinuous quality improvementnewborn screeningplan-do-study-act cyclestimeliness

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Area of Science:

  • Public Health
  • Genetics
  • Healthcare Quality Improvement

Background:

  • Newborn screening (NBS) programs face increasing challenges, including expanded screening panels, new technologies, and workforce shortages.
  • Ensuring timely identification of infants with NBS disorders requires robust continuous quality improvement (CQI).

Purpose of the Study:

  • To assess the effectiveness of a collaborative, data-driven CQI model for improving the national NBS system.
  • To support state NBS programs and research centers in implementing quality improvement (QI) initiatives.

Main Methods:

  • The Health Resources and Services Administration (HRSA) funded the Association of Public Health Laboratories' (APHL) Newborn Screening Technical assistance and Evaluation Program (NewSTEPs) from 2019-2024.
  • NewSTEPs funded 36 QI projects focused on timeliness, result detection, communication, and diagnosis confirmation.
  • A collaborative, data-driven process was employed to guide these QI projects.

Main Results:

  • Thirty-three of the 36 funded QI teams successfully completed their projects.
  • 85% of the completed QI projects achieved their stated goals.
  • The QI Projects Collaborative provided essential funding and resources for NBS quality improvement.

Conclusions:

  • The collaborative model facilitated significant quality improvements within the national NBS system.
  • Technical assistance and a central resource center are effective in sustaining NBS CQI initiatives.
  • This approach demonstrated success in enhancing the overall performance of newborn screening programs.