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Penoscrotal decompression should be considered for prolonged ischaemic priapism
Giuseppe Basile1, David Ralph2,3, Shafi Wardak2
1Department of Urology, Royal Free London Foundation Trust, Great Britain, London, NW3 2QG, United Kingdom.
The Journal of Sexual Medicine
|September 22, 2025
Summary
Penoscrotal decompression (PSD) effectively treats prolonged ischemic priapism (PIP), offering pain relief and detumescence. Early intervention within 36 hours, especially with bilateral procedures, improves success rates for this challenging condition.
Area of Science:
- Urology
- Andrology
- Surgical Innovation
Background:
- Prolonged ischemic priapism (PIP) is a critical condition often leading to erectile dysfunction, particularly when lasting over 48 hours.
- Current treatment options for PIP can be limited, necessitating exploration of effective surgical interventions.
Purpose of the Study:
- To evaluate the surgical and functional outcomes of patients with PIP treated using penoscrotal decompression (PSD).
- To assess the efficacy of a modified PSD technique involving a proximal penile shaft incision.
Main Methods:
- Retrospective analysis of patients with PIP undergoing PSD between 2019 and 2024 across two tertiary centers.
- Comparison of outcomes between bilateral and unilateral PSD, and assessment of success based on timing of presentation.
- Evaluation of surgical success (pain resolution, no recurrence), perioperative results, and sexual function (IIEF-5, penile prosthesis use).
Main Results:
- PSD achieved a 69% success rate, with higher efficacy (73%) in bilateral procedures.
- Immediate detumescence (96%) and pain relief (92%) were commonly observed.
- Treatment success was time-dependent, with superior outcomes when performed within 36 hours; 86% reported satisfactory erectile function post-treatment.
Conclusions:
- Penoscrotal decompression is a safe and effective treatment for prolonged ischemic priapism.
- The modified technique with a penile shaft incision offers advantages in accessibility for urologists.
- Timeliness of intervention (within 36 hours) and bilateral approach are key factors for optimal outcomes in PSD for PIP.

