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Dual-Camera Markerless Motion Capture System for Precise Lower-Limb Kinematic Analysis in Osteoarthritis
Bo Hu1,2,3, Junqing Wang1,2, Wei Xu1,4,5
1Department of Orthopedic Surgery and West China Biomedical Big Data Center, West China Hospital, Sichuan University, 37# Guoxue Road, Chengdu, Sichuan Province, China.
Annals of Biomedical Engineering
|September 22, 2025
Summary
A new dual-camera markerless system accurately measures lower-limb kinematics in osteoarthritis patients. This cost-effective system simplifies biomechanical assessment for clinical use.
Area of Science:
- Biomechanics
- Medical Imaging
- Orthopedics
Background:
- Osteoarthritis (OA) diagnosis and monitoring often rely on accurate lower-limb kinematic analysis.
- Traditional marker-based motion capture systems are effective but costly and complex.
- There is a need for simpler, more accessible methods for kinematic assessment in clinical settings.
Purpose of the Study:
- To develop and validate a dual-camera markerless system for measuring lower-limb kinematics.
- To assess the system's agreement with a gold-standard marker-based motion capture system.
- To evaluate the system's utility for patients with osteoarthritis.
Main Methods:
- A dual-camera markerless system using a neural network-based 2D pose extractor and 3D triangulation was developed.
- Kinematic gait data were collected simultaneously from 152 osteoarthritis patients using both markerless and marker-based systems.
- Agreement was assessed using root mean square distance (RMSD), root mean square error (RMSE), and intraclass correlation coefficient (ICC).
Main Results:
- The markerless system achieved a grand mean RMSD of 11.0 mm and an ICC of 0.95 for keypoints.
- Joint angle analysis showed a mean RMSE of 4.25°.
- ICC values for joint angle waveforms reached 0.90 (sagittal), 0.48 (frontal), and 0.24 (transverse plane).
Conclusions:
- The dual-camera markerless system provides accurate lower-limb kinematic measurements in patient populations.
- The system offers advantages in cost-effectiveness, ease of installation, and reduced expertise requirements.
- This technology facilitates efficient biomechanical assessment for clinical applications.

