Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bipolar Disorder01:30

Bipolar Disorder

628
Bipolar disorder is a chronic mental health condition marked by significant mood fluctuations, including episodes of mania and depression. Elevated energy levels, heightened mood or irritability, impulsive behavior, reduced sleep needs, rapid speech, racing thoughts, inflated self-esteem, and distractibility characterize mania. Individuals with bipolar disorder often alternate between depressive and manic states, with periods of emotional stability lasting an average of six months to a year.
628
Mania and Antimanic Drugs: Overview01:24

Mania and Antimanic Drugs: Overview

561
Mania, a psychological condition characterized by elevated mood, increased energy, and reduced sleep need, is part of the bipolar disorder cycle. The exact cause of mania isn't entirely known, but it is thought to be a combination of genetic, environmental, and neurological factors. Bipolar disorder involves alternating manic and depressive episodes. Mood stabilizers like lithium, antipsychotics, and anticonvulsants help manage these episodes. Lithium carbonate is particularly effective as...
561
Borderline Personality Disorder01:25

Borderline Personality Disorder

535
Borderline Personality Disorder is a complex and multifaceted mental health condition characterized by pervasive instability in interpersonal relationships, self-image, emotions, and impulse control. This instability manifests in extreme emotional reactions, fear of abandonment, and self-destructive behaviors. The disorder significantly impacts daily functioning, often leading to distress in both personal and professional domains.
Genetic and Environmental Contributions
Borderline Personality...
535
Obsessive-Compulsive Disorder01:28

Obsessive-Compulsive Disorder

519
Obsessive-compulsive disorder (OCD) is a mental health condition characterized by recurrent obsessions, compulsions, or both, which consume significant time and interfere with daily functioning. Obsessions involve persistent, intrusive, and unwanted thoughts, images, or urges that evoke anxiety. Common examples include irrational fears of contamination or harm. Compulsions are repetitive behaviors or mental acts performed to reduce the anxiety caused by obsessions. For instance, individuals...
519
Personality Theory by Eysenck and Eysenck01:29

Personality Theory by Eysenck and Eysenck

1.2K
Hans and Sybil Eysenck developed a widely recognized theory of personality, which emphasizes the role of temperament and genetically based differences in shaping individual traits. Their theory posits that biological factors primarily determine personality and can be understood through two main dimensions: extroversion/introversion and neuroticism/stability.
In the extroversion/introversion dimension, highly extroverted people are sociable, outgoing, and easily connect with others. In contrast,...
1.2K
Oppositional Defiant Disorder01:30

Oppositional Defiant Disorder

642
A persistent pattern of angry or irritable mood, defiant behavior, or vindictiveness characterizes Oppositional Defiant Disorder (ODD). Symptoms must occur over at least six months, involve interactions with individuals beyond siblings, and meet specific diagnostic criteria to be clinically significant. The disorder affects emotional regulation, social interactions, and behavior, often manifesting early in life and influencing long-term development and functioning.
Diagnostic Criteria and...
642

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

PSYCHIATRY IN CONTEMPORARY WORLD: NO HEALTH WITHOUT MENTAL HEALTH.

Psychiatria Danubina·2025
Same author

PROMOTING ADOLESCENT MENTAL HEALTH THROUGH SCHOOL-BASED LITERACY INITIATIVES: BEYOND THE STIGMA.

Psychiatria Danubina·2025
Same author

AI AND ALTERNATIVE SYMPTOMS IN THE DIAGNOSIS OF MDD: The role of forgiveness, hopelessness, mixity and diminished drive.

Psychiatria Danubina·2025
Same author

RELATIONSHIP BETWEEN COGNITIVE IMPAIRMENT AND LEFT VENTRICULAR DIASTOLIC DYSFUNCTION IN PATIENTS WITH HEART ARRHYTHMIAS.

Psychiatria Danubina·2025
Same author

THE IMPORTANCE OF HOBBIES TO SUPPORT PHARMACOLOGICAL TREATMENT IN BIPOLAR DISORDER TYPE I AND II: 40 CASES-REPORT IN A GP'S EXPERIENCE.

Psychiatria Danubina·2025
Same author

IMPULSIVITY AND PSYCHIATRIC REHABILITATION INTERVENTIONS: A STUDY ON A SAMPLE OF PATIENTS INCLUDED IN REHABILITATION PROGRAMS.

Psychiatria Danubina·2025

Related Experiment Video

Updated: Jan 17, 2026

Developing a Rat Model for Bipolar Disorder
04:42

Developing a Rat Model for Bipolar Disorder

Published on: May 2, 2025

1.3K

THE CLINICAL NOTION OF RESTLESSNESS AS A LINCHPIN FOR A FULL UNDERSTANDING OF THE BIPOLAR SPECTRUM.

Giuseppe Tavormina1, Francesco Franza2

  • 1Psychiatric Studies Centre "CenStu.Psi", Provaglio d'Iseo (BS), Italy.

Psychiatria Danubina
|September 22, 2025
PubMed
Summary

Restlessness defines a key aspect of thymic disease within the bipolar spectrum. This condition involves significant depressive suffering coupled with anxiety, tension, and somatic symptoms, collectively termed "Restlessness".

Keywords:
bipolar disordersmixed state rating scalemixed statesrestlessness

More Related Videos

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
05:52

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis

Published on: November 21, 2013

15.4K
EEG Mu Rhythm in Typical and Atypical Development
11:50

EEG Mu Rhythm in Typical and Atypical Development

Published on: April 9, 2014

26.5K

Related Experiment Videos

Last Updated: Jan 17, 2026

Developing a Rat Model for Bipolar Disorder
04:42

Developing a Rat Model for Bipolar Disorder

Published on: May 2, 2025

1.3K
Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
05:52

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis

Published on: November 21, 2013

15.4K
EEG Mu Rhythm in Typical and Atypical Development
11:50

EEG Mu Rhythm in Typical and Atypical Development

Published on: April 9, 2014

26.5K

Area of Science:

  • Psychiatry
  • Mood Disorders

Background:

  • Bipolar spectrum disorders often present complex symptom profiles.
  • A significant subset of patients exhibit a
  • mixed picture
  • characterized by overlapping depressive and agitated states.

Purpose of the Study:

  • To define and characterize the concept of
  • Restlessness
  • as a core feature in specific bipolar presentations.
  • To explore the multifaceted nature of depressive suffering when accompanied by agitation and anxiety.

Main Methods:

  • Qualitative analysis of clinical descriptions of patients with bipolar spectrum disorders.
  • Conceptual synthesis of patient-reported symptoms including mood, anxiety, tension, and somatic complaints.

Main Results:

  • Identified
  • Restlessness
  • as a unifying concept for a specific presentation within the bipolar spectrum.
  • Highlighted that depressive suffering in these cases is invariably accompanied by internal anxiety, muscular tension, irritability or apathy, existential anguish, and somatic symptoms.

Conclusions:

  • Restlessness
  • is a crucial descriptor for understanding a significant subtype of bipolar disorder.
  • Recognizing this complex symptom cluster is vital for accurate diagnosis and effective treatment of mood disorders.