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Updated: Jan 17, 2026

Mouse Models of Epididymitis Induced by Pathogen-Associated Molecular Patterns
Published on: December 12, 2025
Tuberculous epididymo-orchitis mimicking testicular cancer: a diagnostic challenge
H Balabhaskar1, Manu Mk2, Manu Jose Chirayath3
1Urology, Trivandrum Medical College, Thiruvananthapuram, India balabhaskarh@gmail.com.
Abstract:
A patient in his early 60s with a long-standing history of scrotal swelling and recent onset of pain underwent high inguinal orchidectomy due to a suspected testicular malignancy. Tumour markers were normal, but histopathological examination revealed caseating granulomas, confirming tuberculous epididymo-orchitis. He was diagnosed with genitourinary tuberculosis and initiated on anti-tubercular therapy. The patient responded well to treatment with no recurrence. This case highlights the importance of considering tuberculosis in the differential diagnosis of testicular lesions and the critical role of histopathology in confirming the diagnosis.
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