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Related Concept Videos

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Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
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Updated: Jan 17, 2026

Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery
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Pain in social context: a systematic review protocol.

Nicolas Ureña Bautista1, Rafael Serrano-Del-Rosal2, Gema Serrano-Gemes3

  • 1Institute for Advanced Social Studies, Spanish National Research Council (IESA-CSIC), Córdoba, Spain.

BMJ Open
|September 22, 2025
PubMed
Summary
This summary is machine-generated.

This review examines how social factors influence pain perception. It highlights the need for better integration of social dimensions in pain research to advance understanding and interventions.

Keywords:
Clinical ProtocolsPAIN MANAGEMENTSystematic Review

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Area of Science:

  • Social Sciences
  • Medical Research
  • Psychology

Background:

  • Pain is a complex, multidimensional experience influenced by social conditioning.
  • The biopsychosocial model acknowledges pain's complexity, yet its social dimension is under-researched.
  • Standardized criteria for evaluating the social dimension of pain are lacking, hindering empirical integration.

Purpose of the Study:

  • To systematically review and analyze how pain studies incorporate the social dimension.
  • To understand the extent to which cultural, relational, and contextual factors are accounted for in pain research.
  • To identify gaps in the literature regarding the social aspects of pain perception and experience.

Main Methods:

  • Systematic review of empirical and theoretical studies in English and Spanish.
  • Searches conducted across five major databases: PubMed, Web of Science, Scielo, Scopus, and CINAHL.
  • Two-phase study selection (title/abstract, then full-text) with bespoke data extraction and quality assessment tools.

Main Results:

  • (Results not yet available as this is a protocol.)
  • (Results not yet available as this is a protocol.)
  • (Results not yet available as this is a protocol.)

Conclusions:

  • (Conclusions not yet available as this is a protocol.)
  • (Conclusions not yet available as this is a protocol.)
  • (Conclusions not yet available as this is a protocol.)