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Development of a Universal In Vivo Predictive Dissolution Method for a Borderline BCS III/IV Drug Guided by Modeling

Mauricio A García1, Fernando Tapia1, Benjamín Escares1,2

  • 1Departamento de Farmacia, Escuela de Química y Farmacia, Facultad de Química y de Farmacia, Pontificia Universidad Católica de Chile, Vicuña Mackenna 4860, Campus San Joaquín, Macul, Santiago 7820436, Chile.

Molecular Pharmaceutics
|September 22, 2025
PubMed

Keywords:
PBPKin vivo predicted dissolutionnonsink dissolutionsmall volume dissolution testingvirtual bioequivalence

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